MICROEMULSION & SUB-MICRON EMULSION PROCESS & COMPOSITIONS

摘要

An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient comprising an oil phase dispersed throughout a water phase, said oil phase including at least one of the group consisting of animal, mineral or vegetable oils, silanes, siloxanes, esters, fatty acids, fats, halogen compounds, and alkoxylated alcohols; and at least one lipophilic surfactant; and said water phase including at least one hydrophilic surfactant, water and optionally non-surfactant amphiphilic compound, the weight ratio of the at least one hydrophilic surfactant to the at least one lipophilic surfactant being approximately 9.0:1.0 to 2.0:3.0.