发明名称 ISOLATED MONOCLONAL ANTIBODIES OR ANTIGEN BINDING FRAGMENTS THEREOF THAT BIND TO A HUMAN TRAIL-R POLYPEPTIDE
摘要 A protein designated TRAIL receptor binds the protein known as TNF-Related Apoptosis-Inducing Ligand (TRAIL). The TRAIL receptor finds use in purifying TRAIL or inhibiting activities thereof. Isolated DNA sequences encoding TRAIL-R polypeptides are provided, along with expression vectors containing the DNA sequences, and host cells transformed with such recombinant expression vectors. Antibodies that are immunoreactive with TRAIL-R are also provided.
申请公布号 IL131030(A) 申请公布日期 2011.02.28
申请号 IL19990131030 申请日期 1999.07.21
申请人 IMMUNEX CORPORATION 发明人
分类号 C12N15/09;A61K38/00;A61P43/00;C07K14/705;C07K14/715;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/08 主分类号 C12N15/09
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