发明名称 |
USE OF A BIS-MALEIC ANHYDRIDE CROSS-LINKING AGENT FOR FIXATION OF A CELL OR TISSUE SAMPLE |
摘要 |
The present invention relates to novel bis-maleic anhydrides. It especially relates to the discovery that bis-maleic anhydride cross-linking agents can be used for preservation/fixation of a cell or tissue sample. With great advantage a bis-maleic anhydride cross-linking agent can be used in methods requiring fixation of a cell or tissue sample and at the same time requiring that the fixative has little impact on the later detection of a protein or a nucleic acid in procedures like immunohistochemistry, fluorescence in situ hybridization or RT-PCR. |
申请公布号 |
CA2770545(A1) |
申请公布日期 |
2011.02.24 |
申请号 |
CA20102770545 |
申请日期 |
2010.08.19 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
JOSEL, HANS-PETER;GERG, MICHAEL;HERRMANN, RUPERT;SAEZ DIAZ, ROSA ISABEL |
分类号 |
G01N1/30 |
主分类号 |
G01N1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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