发明名称 |
Electrochemical biosensors, applications and methods of making biosensors |
摘要 |
Electrochemical biosensors, methods of making biosensors and methods of detecting a target analyte in a sample to be analyzed are provided. A preferred embodiment device comprises a non-conductive polymer deposited on the electrode to form a matrix material having a plurality of pores; a capture biomolecule immobilized on the electrode such that the binding of the target analyte to the capture biomolecule effectively blocks a sufficient number of pores in the matrix material to produce a measurable decrease in the rate of a redox reaction occurring at the electrode; a current source for driving a redox reaction at the electrode; a redox species in contact with the electrode; and a detector element operatively connected to the electrode to detect the measureable decrease of a change in the rate of a redox reaction occurring due to the blockage of pores in the matrix material by the target analyte.
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申请公布号 |
US7892414(B1) |
申请公布日期 |
2011.02.22 |
申请号 |
US20050274709 |
申请日期 |
2005.11.15 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF ARMY |
发明人 |
SUMNER JAMES J. |
分类号 |
G01N27/327;G01N27/26 |
主分类号 |
G01N27/327 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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