发明名称 |
Chemokine-binding protein and methods of use |
摘要 |
Described herein are chemokine-binding domains of THAP-family polypeptides and pharmaceutical compositions which include a polypeptide comprising a chemokine-binding domain of a THAP-family polypeptide. Also disclosed are methods of binding chemokines, inhibiting the activity of chemokines, detecting chemokines, and reducing the symptoms associated with a chemokine mediated or influenced condition by contacting the chemokine with an agent that includes a polypeptide comprising a chemokine binding domain of a THAP-family polypeptide.
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申请公布号 |
US7892727(B2) |
申请公布日期 |
2011.02.22 |
申请号 |
US20060417317 |
申请日期 |
2006.05.03 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS |
发明人 |
GIRARD JEAN-PHILIPPE;ROUSSIGNE MYRIAM;AMALRIC FRANCOIS |
分类号 |
C12Q1/00;A61K38/19;A61K39/395;C07K14/47;C12N15/00;G01N33/00;G01N33/53;G01N33/68 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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