发明名称 Oestrogen derivatives as inhibitors of steroid sulphatase
摘要 The present invention provides a compound comprising a steroidal ring system and an optional group R1 selected from any one of —OH, a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein the D ring of the steroidal ring system is substituted by a group R2 of the formula -L-R3, wherein L is an optional linker group and R3 is selected from groups which are or which comprise one of a nitrite group, an alcohol, an ester, an ether, an amine and an alkene, provided that when R3 is or comprises an alcohol, L is present; and wherein the A ring of the steroidal ring system is substituted at position 2 or 4 with a group R4, wherein R4 is a hydrocarbyl group.
申请公布号 US7893284(B2) 申请公布日期 2011.02.22
申请号 US20050233945 申请日期 2005.09.23
申请人 STERIX LIMITED 发明人 LEESE MATTHEW;PUROHIT ATUL;REED MICHAEL JOHN;NEWMAN SIMON PAUL;CHANDER SURINDER KUMAN;JOURDAN FABRICE;POTTER BARRY VICTOR LLOYD
分类号 C07J3/00;A61K31/56;C07J1/00;C07J41/00;C07J43/00 主分类号 C07J3/00
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