| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to novel pyrrolidinium derivatives of formula I ^ in enantiomer form or pharmaceutically acceptable salt thereof, where R1 and R3 each independently denotes cyclopentyl, cyclohexyl, phenyl; R2 denotes OH; R4 denotes C1-C4alkyl; R5 denotes C1alkyl, substituted with a CO-NH-R6 group; R6 denotes a 5-member unsaturated heterocyclic group containing one N atom and one O atom in the ring, a 6-member heterocyclic group containing two N atoms in the ring. ^ EFFECT: compounds can inhibit binding of aceylcholine with M3 muscarinic receptors, which facilitates their use in a pharmaceutical composition. ^ 6 cl, 3 tbl, 8 ex |
