发明名称 |
SOLID ORAL FORMULATIONS AND CRYSTALLINE FORMS OF AN INHIBITOR OF APOPTOSIS PROTEIN |
摘要 |
The present disclosure relates to crystalline form of (S)-N-((S)-1- cyclohexyl-2-{(S)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)- 2-methylamino-propionamide, salts and hydrates thereof. This disclosure also relates to solid oral formulation of (S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-(4-fluoro- benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide, pharmaceutically acceptable salts, solvates (including hydrates) thereof, as well as methods of treatment using the same. |
申请公布号 |
WO2011018474(A1) |
申请公布日期 |
2011.02.17 |
申请号 |
WO2010EP61679 |
申请日期 |
2010.08.11 |
申请人 |
NOVARTIS AG;THAKUR, JEEWAN;YANG, DONG;FENG, LILI |
发明人 |
THAKUR, JEEWAN;YANG, DONG;FENG, LILI |
分类号 |
C07D417/04;A61K9/20;A61K9/28;A61K31/427 |
主分类号 |
C07D417/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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