Vaccine composition comprising conjugated native N. Meningitidis capsular polysaccharides

摘要

The present application discloses an immunogenic composition comprising N . meningitidis capsular polysaccharides from at least one of serogroups A, C, W135 and Y conjugated to a carrier protein to produce a N. meningitidis capsular polysaccharide conjugate, wherein the average size of each N. meningitidis polysaccharide is above 50kDa.