发明名称 Formulation for adenovirus storage
摘要 The present invention addresses the need to improve the long-term storage stability (i.e. infectivity) of vector formulations. In particular, it has been demonstrated that for adenovirus, the use of bulking agents, cryoprotectants and lyoprotectants imparts desired properties that allow both lyophilized and liquid adenovirus formulations to be stored at 4° C. for up to 6 months and retain an infectivity between 60-100% of the starting infectivity.
申请公布号 US7888097(B2) 申请公布日期 2011.02.15
申请号 US20070926854 申请日期 2007.10.29
申请人 CRUCELL HOLLAND B.V. 发明人 WU ZHENG;ZHANG SHUYUAN
分类号 C12N7/00;A61K9/19;A61K35/76;A61K47/02;A61K47/18;A61K47/20;A61K47/26;A61K47/32;A61K47/38;A61K47/42;A61K47/46;A61K48/00;C12N1/04;C12N15/861 主分类号 C12N7/00
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