发明名称 |
Novel vaccine containing adjuvant capable of inducing mucosal immunity |
摘要 |
<p>The present invention provides an adjuvant that possesses a greater adjuvant potential than that of a conventional adjuvant, and that is capable of producing a protective reaction across different strains. This problem has been solved by the finding that a double-stranded RNA (for example, Poly(I:C)) unexpectedly exhibits the above capability when used in combination with a subunit antigen. Accordingly, the present invention provides a vaccine for mucosal administration containing A) a double-stranded RNA and B) a subunit antigen or inactivated antigen of a pathogen.</p> |
申请公布号 |
AU2004263037(B2) |
申请公布日期 |
2011.02.10 |
申请号 |
AU20040263037 |
申请日期 |
2004.08.10 |
申请人 |
THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OFOSAKA UNIVERSITY;JAPAN AS REPRESENTED BY THE DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES;TORAY INDUSTRIES, INC. |
发明人 |
TAKEFUMI TANIMOTO;TETSUTAROU SATA;HIDEKI HASEGAWA;TAKESHI KURATA;SHIN-ICHI TAMURA;MASAMI MORIYAMA |
分类号 |
A61J7/04;A61K39/145;A61K31/7105;A61K39/00;A61K39/09;A61K39/095;A61K39/10;A61K39/102;A61K39/106;A61K39/12;A61K39/135;A61K39/20;A61K39/235;A61K39/245;A61K39/25;A61K39/39;A61K48/00;A61P31/04;A61P31/12;A61P31/16;A61P31/18;A61P31/22;A61P37/02 |
主分类号 |
A61J7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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