| 发明名称 |
MEDICINE COMPRISING BICYCLIC HETEROCYCLIC DERIVATIVE |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a medicine comprising a bicyclic heterocyclic derivative effective as a renin inhibitor. SOLUTION: There is provided a medicine comprising a compound of formula (I) or its pharmacologically acceptable salt. In the formula, R<SP>1a</SP>is halogen atom or the like; R<SP>1m</SP>is hydrogen atom or the like; G<SP>1</SP>is -N(R<SP>1b</SP>)- or the like; G<SP>2</SP>is -CO- or the like; G<SP>3</SP>is -C(R<SP>1c</SP>)(R<SP>1d</SP>)- or the like; G<SP>4</SP>is oxygen atom or the like; R<SP>1b</SP>is optionally substituted 1-6C alkyl or the like; R<SP>1c</SP>and R<SP>1d</SP>are each independently same or different hydrogen atom or the like; R<SP>2</SP>is hydrogen atom, optionally substituted 1-6C alkyl or the like; R<SP>3a</SP>, R<SP>3b</SP>, R<SP>3c</SP>and R<SP>3d</SP>are each independently same or different group: -A-B (A is single bond or the like; and B is hydrogen atom or the like), or the like; and n is 1 or the like. COPYRIGHT: (C)2011,JPO&INPIT
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| 申请公布号 |
JP2011026301(A) |
申请公布日期 |
2011.02.10 |
| 申请号 |
JP20100142080 |
申请日期 |
2010.06.22 |
| 申请人 |
DAINIPPON SUMITOMO PHARMA CO LTD |
发明人 |
NAKAHIRA HIROYUKI;IKUMA YOHEI;FUKUDA NOBUHISA;YOSHIDA KOZO;KIMURA HIDENORI;SUETSUGU SEI;FUSANO AKIRA;SAWAMURA KIYOTO;IKEDA JUNYA;NAKAI YOSHIO |
| 分类号 |
A61K31/538;A61K31/454;A61K31/4709;A61K31/5415;A61P7/00;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P25/06;A61P25/28;A61P27/02;A61P27/06;A61P43/00 |
主分类号 |
A61K31/538 |
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