摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a nucleic acid specifically accumulating in an organ. <P>SOLUTION: After a nucleic acid candidate is administered to an animal, a nucleic acid candidate specifically accumulated in an organ is collected from the organ of the animal as an objective nucleic acid. Using this nucleic acid with a tag nucleic acid for delivery, administration of a complex between the tag nucleic acid and a delivery object allows the delivery object to be specifically delivered to an organ similar to the organ in which the nucleic acid has been collected. For example, an aptamer is preferably used as the nucleic acid candidate. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |