发明名称 |
GALENIC COMPOSITION CONTAINING OPIOID ANTAGONISTS |
摘要 |
A pharmaceutical composition for oral administration contains naloxone-, N-methylnaloxone- and/or N-methylnaltrexone-containing particles which release the active substance depending on the ambient pH. This ensures the liberation of the active substance over the whole gastrointestinal tract. The side effects caused by the use of analgesic opioids, such as constipation, are thus eliminated without reducing the analgesic effect.
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申请公布号 |
CA2273353(C) |
申请公布日期 |
2011.02.08 |
申请号 |
CA19972273353 |
申请日期 |
1997.12.04 |
申请人 |
KLINGE PHARMA GMBH |
发明人 |
WALTER, KERSTEN;PROFITLICH, THOMAS |
分类号 |
A61K9/16;A61K31/485;A61K9/20;A61K9/26;A61K9/48;A61K9/50;A61K9/52;A61K9/54;A61P1/10 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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