发明名称 |
GEL COMPOSITION AND METHODS |
摘要 |
Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 or less for systemic applications and systems releasing 10 % or less of the total dose of beneficial agent in the first 24 hours after implantation for local applications. The compositions include a biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
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申请公布号 |
CA2275525(C) |
申请公布日期 |
2011.02.08 |
申请号 |
CA19972275525 |
申请日期 |
1997.12.18 |
申请人 |
ALZA CORPORATION |
发明人 |
BRODBECK, KEVIN J.;GAYNOR-DUARTE, ANN T.;SHEN, THEODORE T. |
分类号 |
A61K9/00;A61K9/14;A61K31/70;A61K38/00;A61K38/21;A61K38/27;A61K38/47;A61K47/02;A61K47/10;A61K47/14;A61K47/34 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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