Antigen presenting system and methods for activation of t-cells

摘要

The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8⁺ T-cells to produce cytokines and become cytotoxic.