METHOD FOR IMMOBILIZING LIGANDS OR COMPOUNDS HAVING LIGANDS BONDED THERETO

摘要

There is provided a method for immobilizing a ligand by reacting a solvent-insoluble carrier having aldehyde group with a compound shown by the general formula: wherein X is -S- or -O-, R<1>, R<2> and R<6> are the same or different, each of which is hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R<3> is hydrogen atom or a substituent wherein an atom adjacent to nitrogen atom shown in the above-mentioned general formula has no unsaturated bond, R<4>, R<5> and R<7> are arbitrary substituents; provided that only one partial chemical structure of HX-C-C-NHR<3> wherein X and R<3> are the same as defined above or HX-C-C-C-NHR<3> wherein X and R<3> are the same as defined above is contained in one compound described above by which, a ligand or a compound to which a ligand is bonded can react specifically and effectively with aldehyde group in a solvent-insoluble carrier at a prescribed position to form a stable bond.