发明名称 Caprolactams and their use as anti-inflammatory agents
摘要 <p>The invention relates inter alia to a compound of general formula (I) or (I'): wherein X is -CO-R 1 or -SO 2 -R 2 , R 1 is an alkyl, haloalkyl, alkoxy, haloalkoxy, alkenyl, alkynyl or alkylamino radical of 4 to 20 carbon atoms (for example of 5 to 20 carbon atoms, of 8 to 20 carbon atoms, of 9 to 20 carbon atoms, of 10 to 18 carbon atoms, of 12 to 18 carbon atoms, of 13 to 18 carbon atoms, of 14 to 18 carbon atoms, of 13 to 17 carbon atoms.); and R 2 is an alkyl radical of 4 to 20 carbon atoms (for example of 5 to 20 carbon atoms, of 8 to 20 carbon atoms, of 9 to 20 carbon atoms, of 10 to 18 carbon atoms, of 12 to 18 carbon atoms, of 13 to 18 carbon atoms, of 14 to 18 carbon atoms, and of 13 to 17 carbon atoms); or alternatively R 1 and R 2 are selected independently from a peptido radical having from 1 to 4 peptidic moieties linked together by peptide bonds.</p>
申请公布号 EP2279741(A2) 申请公布日期 2011.02.02
申请号 EP20100011516 申请日期 2004.11.30
申请人 CAMBRIDGE ENTERPRISE LTD. 发明人 GRAINGER, DAVID JOHN;FOX, DAVID JOHN
分类号 A61K31/55;A61P19/10;A61P25/28;A61P29/00;A61P37/00;C07D223/10;C07K5/06 主分类号 A61K31/55
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