Disclosed is a process for preparing macrocyclic compounds of formula (I) which comprises the steps of reacting a macrocyclic compound of formula (3) with a bicyclic compound (QUIN), wherein the substituents are disclosed within the specification. The intermediate, QUIN, is also disclosed as well as a process for preparing the said QUIN compound. The use of the macrocyclic intermediate of formula (3) for preparing a compound of formula (I) via the claimed process is also disclosed.
申请公布号
NZ562167(A)
申请公布日期
2011.01.28
申请号
NZ20060562167
申请日期
2006.03.06
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人
BUSACCA, CARL ALAN;GALLOU, FABRICE;HADDAD, NIZAR;HOSSAIN, AZAD;KAPADIA, SURESH R;LIU, JIANXIU;SENANAYAKE, CHRIS HUGH;WEI, XUDONG;YEE, NATHAN K