METHOD FOR OBTAINING MYOFIBROBLASTS

摘要

The invention relates to a method for obtaining myofibroblasts. According to said method: (a) a sample of cells including essentially fibroblasts is prepared; and (b) said sample of cells is cultivated in a serum-free culture medium. The main purpose of the invention is to obtain a population of myofibroblasts with characteristics that enable said cells to be studied and, in particular, a population with the highest possible myofibroblast purity. The invention can be implemented for the following uses, among others: identification of myofibroblast biomarkers, identification of therapeutic targets, identification and validation of antineoplastic compounds, in vitro model for screening pharmaceutical or cosmetic compounds.