| 发明名称 |
SULFONAMIDES AS ZAP-70 INHIBITORS |
| 摘要 |
<p>The invention relates to compounds of formula (I) wherein R1 to R9 and R4a have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of ZAP-70 for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.</p> |
| 申请公布号 |
EP2276747(A1) |
申请公布日期 |
2011.01.26 |
| 申请号 |
EP20090718767 |
申请日期 |
2009.03.10 |
| 申请人 |
CELLZOME LIMITED |
发明人 |
MAJOR, JEREMY;HARRISON, RICHARD, JOHN;RAMSDEN, NIGEL;MIDDLEMISS, DAVID;KRUSE, ULRICH;DREWES, GERARD |
| 分类号 |
C07D239/48;A61K31/505;A61K31/506;A61K31/5377;A61K31/538;A61P37/06;A61P37/08;C07D401/12;C07D403/12;C07D407/12;C07D409/12;C07D413/12;C07D417/12 |
主分类号 |
C07D239/48 |
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