| 发明名称 |
Stable crystalline salt of 5-methyl-(6S)-tetrahydrofolic acid |
| 摘要 |
Crystalline salts of 5-methyl-(6R,S)-, -(6S)- and -(6R)-tetrahydrofolic acid are new. Independent claims are also included for: (1) crystalline calcium salt of 5-methyl-(6S)- and -(6R)-tetrahydrofolic acid; and (2) the preparation of crystalline salts of 5-methyl-(6R,S)-, -(6S)- and 5-methyl-(6R)-tetrahydrofolic acid. |
| 申请公布号 |
EP2189459(B1) |
申请公布日期 |
2011.01.19 |
| 申请号 |
EP20090178426 |
申请日期 |
2000.04.08 |
| 申请人 |
MERCK EPROVA AG |
发明人 |
MUELLER, HANS RUDOLF;EGGER, THOMAS;MOSER, RUDOLF |
| 分类号 |
C07D471/04;C07D475/04;A23L33/15;A61K31/519;A61K31/522;A61P3/02;A61P7/06;A61P35/00;A61P39/02 |
主分类号 |
C07D471/04 |
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