发明名称 IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE
摘要 There is provided an imidazole derivative useful as a thrombosis treating agent, which is represented by the formula (I): wherein R represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent linear hydrocarbon group, X represents an optionally substituted divalent hydrocarbon group, Y represents —CO—, —S(O)—, —S(O)2— or a bond, ring A represents an optionally substituted pyrrolidine ring, an optionally substituted piperidine ring or an optionally substituted perhydroazepine ring, Z1 and Z3 independently represent a bond or an optionally substituted divalent linear hydrocarbon group, Z2 represents —N(R1)—, —O—, —S(O)—, —S(O)2—, —CO—, —CH(R1)— or a bond, ring B represents an optionally substituted imidazole ring, wherein a substituent which the optionally substituted imidazole ring represented by ring B may have may be taken together with R1 to form an optionally substituted ring, and a represents 0, 1 or 2.
申请公布号 US2011009389(A1) 申请公布日期 2011.01.13
申请号 US20100879798 申请日期 2010.09.10
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 KUBO KEIJI;KUROITA TAKANOBU;IMAEDA YASUHIRO;KAWAMURA MASAKI
分类号 A61K31/55;A61K31/4439;A61K31/454;A61K31/4545;A61K31/4985;A61K31/519;A61P7/02;A61P9/00;A61P9/10;A61P43/00;C07D401/04;C07D401/12;C07D401/14;C07D471/04;C07D487/04;C07D498/04;C07D513/04 主分类号 A61K31/55
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