发明名称 |
ANTI-FLT3 ANTIBODIES |
摘要 |
The present invention provides fully human antibodies that specifically bind to human FLT3 within extracellular domains 4 or 5 with high affinity. The invention further provides methods of treating leukemia by administering an effective amount of an antibody either alone or in combination with an anti-cancer agent or treatment including methotrexate. |
申请公布号 |
US2011008355(A1) |
申请公布日期 |
2011.01.13 |
申请号 |
US20100890793 |
申请日期 |
2010.09.27 |
申请人 |
IMCLONE LLC |
发明人 |
LI YIWEN;LU DAN;TONRA JAMES ROBERT;SURGULADZE DAVID |
分类号 |
A61K39/395;A61P35/00;A61P35/02;C07H21/04;C07K16/18;C12N5/10;C12N15/63;C12P21/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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