发明名称 |
Modulation of negative immune regulators and applications for immunotherapy |
摘要 |
The invention includes compositions and methods for enhancing immunopotency of an immune cell by way of inhibiting a negative immune regulator in the cell. The present invention provides vaccines and therapies in which antigen presentation is enhanced through inhibition of negative immune regulators. The present invention also provides a mechanism to break self tolerance in tumor vaccination methods that rely on presentation of self tumor antigens.
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申请公布号 |
US7868159(B2) |
申请公布日期 |
2011.01.11 |
申请号 |
US20060335736 |
申请日期 |
2006.01.19 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
CHEN SI-YI;EVEL-KABLER KEVIN C.;SONG XIAOTONG;HUANG XUE F.;SHARABI ANDREW |
分类号 |
C07H21/04 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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