发明名称 Modulation of negative immune regulators and applications for immunotherapy
摘要 The invention includes compositions and methods for enhancing immunopotency of an immune cell by way of inhibiting a negative immune regulator in the cell. The present invention provides vaccines and therapies in which antigen presentation is enhanced through inhibition of negative immune regulators. The present invention also provides a mechanism to break self tolerance in tumor vaccination methods that rely on presentation of self tumor antigens.
申请公布号 US7868159(B2) 申请公布日期 2011.01.11
申请号 US20060335736 申请日期 2006.01.19
申请人 BAYLOR COLLEGE OF MEDICINE 发明人 CHEN SI-YI;EVEL-KABLER KEVIN C.;SONG XIAOTONG;HUANG XUE F.;SHARABI ANDREW
分类号 C07H21/04 主分类号 C07H21/04
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