发明名称 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
摘要 Process for the synthesis of ivabradine of formula (I): addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof. α crystalline form of ivabradine hydrochloride. Medicinal products containing α crystalline form of ivabradine hydrochloride, which are useful as bradycardics.
申请公布号 US7867994(B2) 申请公布日期 2011.01.11
申请号 US20070654719 申请日期 2007.01.18
申请人 LES LABORATOIRES SERVIER 发明人 LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;SOUVIE JEAN-CLAUDE;BRIGOT DANIEL;HORVATH STEPHANE;AUGUSTE MARIE-NOELLE;DAMIEN GERARD
分类号 C07D223/16;A61K31/55;A61P9/00;A61P9/04;A61P9/06;A61P9/10;C07D405/06 主分类号 C07D223/16
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