摘要 |
Disclosed are compounds of general formula (I) in which A is a group of formula (a) or (b) where R represents hydrogen or a halogen atom, an S(O)z(C1-C4)alkyl group, an -NHSO2(C1-C4)alkyl group, an -SO2NH-(C1-C4)alkyl group, an NHSO2phenyl-(C1-C4)alkyl group or an NHSO2phenyl group, said phenyl being substituted with a halogen atom or with a (C1-C4)alkoxy group; R1 represents hydrogen atom or a (C1-C4)alkyl group, a -CO(C1-C4)alkyl group, a phenyl(C1-C4)alkyl group or a -CO-phenyl group, said phenyl being substituted with a halogen atom or with a (C1-C4)alkoxy group; R2 is hydrogen atom, an -SO2(C1-C4)alkyl group, an -SO2phenyl-(C1-C4)alkyl group or -SO2phenyl group; X completes a ring of 5 to 8 atoms, said ring being saturated or unsaturated, possibly being substituted with one or two (C1-C4)alkyl groups and bearing one or two carbonyl groups; n, m and z are independently 0, 1 or 2. The meaning of other substituents is disclosed in the description. Also disclosed are salts and solvates of aforementioned compounds, pharmaceutical compositions containing them, process of their preparation and intermediates for said process. |