PREDICTING AMD WITH SNPS WITHIN OR NEAR C2, FACTOR B, PLEKHA1, HTRA1, PRELP, OR LOC387715

摘要

Gene polymorphisms and genetic profiles associated with an elevated or a reduced risk of a complement cascade dysregulation disease such as AMD are disclosed. Methods and reagents for determination of risk, diagnosis and treatment of such diseases are provided, as well as methods and reagents for determining sequence variants in the genome of an individual which facilitate assessment of risk for developing such diseases are provided.