HYALURONIC ACID BINARY MIXTURES AND THERAPEUTIC USE THEREOF

摘要

The present invention is related to hyaluronic acid compositions consisting in a binary mixtures of hyaluronic acid samples having mainly different weight-average molecular weight and then different rheological properties in aqueous solution. The resulting compositions have demonstrated peculiar rheological behaviour with a balance between viscosity and viscoelasticity. Accordingly, these compositions of hyaluronic acid are useful for treatment of joint diseases by intra-articular administration or extra-articular application in soft tissue disorders.