发明名称 |
PROTEIN-ASSISTED DRUG DELIVERY SYSTEM FOR THE TARGETED ADMINISTRATION OF ACTIVE AGENTS |
摘要 |
The present invention provides a composition and prodrug for targeted drug delivery to the central nervous system of a patient. The inventive composition and prodrug include a pharmaceutically acceptable active agent and at least one protein selected from the group consisting of a fimbrial adhesin protein, a membrane protein, and combinations thereof. The inventive compositions and prodrugs of the present invention selectively target the blood-brain barrier and deliver hydrophilic and lipophilic active agents of varying sizes to the central nervous system.
|
申请公布号 |
US2010330158(A1) |
申请公布日期 |
2010.12.30 |
申请号 |
US20100748221 |
申请日期 |
2010.03.26 |
申请人 |
INNOPHARMA, LLC |
发明人 |
SONI VISHAL;PATEL KANAIYALAL R.;LAKKARAJU DASARADHI;PURI NAVNEET |
分类号 |
A61K9/127;A61K38/00;A61P25/00 |
主分类号 |
A61K9/127 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|