NOVEL METHOD FOR QUANTIFYING PROTEINS BY MASS SPECTROMETRY
摘要
<p>The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amount of target protein in the sample, characterized in that the selected first-generation fragment ion having a mass (m/z)2 is a doubly-charged peptide having a proline and/or a histidine in position 1.</p>
申请公布号
WO2010136706(A1)
申请公布日期
2010.12.02
申请号
WO2010FR50991
申请日期
2010.05.21
申请人
BIOMERIEUX;UNIVERSITE CLAUDE BERNARD LYON I;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;LEMOINE, JEROME;SALVADOR, ARNAUD;CHARRIER, JEAN-PHILIPPE;FORTIN, TANGUY