A COMPOSITION COMPRISING (-) -TRANS-3- (5, 6-DIHYDRO-4H-PYRROLO [3,2,1-IJ] QUINOLIN-L-YL)-4-(LH-INDOL-3-YL) PYRROLIDINE- 2, 5-DIONE IN COMBINATION WITH A SECOND ANTI-PROLIFERATIVE AGENT
摘要
The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or a pyrroloquinolinyl-pyrrolidine-2,5-dione compound in combination with a therapeutically effective amount of a second anti-proliferative agent.
申请公布号
WO2010093789(A3)
申请公布日期
2010.12.02
申请号
WO2010US23893
申请日期
2010.02.11
申请人
ARQULE, INC.;KYOWA HAKKO KIRIN CO., LTD.;CHAN, THOMAS, C. K.;FRANCE, DENNIS, S.;ISHII, KENICHI;PUCCI, PAOLO
发明人
CHAN, THOMAS, C. K.;FRANCE, DENNIS, S.;ISHII, KENICHI;PUCCI, PAOLO