PHARMACEUTICAL COMPOSITION COMPRISING PROSTAGLANDIN DERIVATIVES FOR USE IN MODULATING CLAUDIN MEDIATED FUNCTIONS AND IN THE TREATMENT OF DERMATOLOGICAL DISORDERS

摘要

Disclosed is a pharmaceutical composition for modulating a claudin-mediated function in a mammalian subject which comprises administering to a subject in need thereof an effective amount of a specific fatty acid derivative. The application also discloses a method for treating a dermatological disease and a method for modulating an expression of a claudin in a mammalian subject using the same fatty acid derivative as above.