发明名称 |
METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEIN AND PEPTIDE THERAPEUTIC AGENTS |
摘要 |
The present invention provides a pharmaceutical composition formulated for oral delivery, comprising a particulate non-covalently associated mixture of pharmacologically inert silica nanoparticles having a hydrophobic surface, a polysaccharide, and a biologically active protein or peptide suspended in an oil. The present invention further provides methods of manufacturing same and therapeutic methods utilizing same for oral delivery of a therapeutic protein or peptide. |
申请公布号 |
US2010297245(A1) |
申请公布日期 |
2010.11.25 |
申请号 |
US20090811871 |
申请日期 |
2009.01.08 |
申请人 |
OSHADI DRUG ADMINISTRATION LTD. |
发明人 |
VOL ALEXANDER;GRIBOVA ORNA |
分类号 |
A61K9/14;A61K38/18;A61K38/19;A61K38/21;A61K38/23;A61K38/27;A61K38/46;A61K39/395;A61P17/18;A61P35/00 |
主分类号 |
A61K9/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|