发明名称 REPAIR AND TREATMENT OF BONE DEFECT USING AGENT PRODUCED BY CHONDROCYTES CAPABLE OF HYPERTROPHICATION AND SCAFFOLD
摘要 The present invention provides a composite material for promoting or inducing osteogenesis in a biological organism. The composite material includes: A) an induced osteoblast differentiation inducing agent obtained by culturing chondrocytes capable of hypertrophication in a differentiation agent producing medium containing dexamethasone, &bgr;-glycerophosphate, ascorbic acid and a serum component; and B) a biocompatible scaffold. The present invention also provides a method of producing this composite material and a method of promoting or inducing osteogenesis in a biological organism.
申请公布号 US2010297210(A1) 申请公布日期 2010.11.25
申请号 US20080665318 申请日期 2008.06.20
申请人 HOYA CORPORATION 发明人 OKIHANA HIROYUKI
分类号 A61K9/00;A61K35/12;A61K38/18;A61P19/00 主分类号 A61K9/00
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