发明名称 |
PROCESS FOR PROVIDING A TEMPERATURE-STABLE MUSCLE RELAXANT ON THE BASIS OF THE NEUROTOXIC COMPONENT OF BOTULINUM TOXIN |
摘要 |
The present invention provides a method for providing a muscle relaxant, wherein said muscle relaxant is a reconstituted solution comprising the neurotoxic component of botulinum toxin free of complexing proteins, which exhibits at least one of the following characteristics, more preferably all characteristics a) to d): a. Stable at storage temperatures above 20° C. b. Stable in the presence of preservatives and/or analgesics c. Resistant against "freeze and thaw"-cycles d. Stable if stored in containers of different material. |
申请公布号 |
ZA200907875(B) |
申请公布日期 |
2010.11.24 |
申请号 |
ZA20090007875 |
申请日期 |
2009.11.10 |
申请人 |
MERZ PHARMA GMBH & CO KGAA, |
发明人 |
EISELE KARL;TAYLOR HAROLD V;MARX MATTHIAS |
分类号 |
C07K;A61K |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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