| 发明名称 |
Single-chain multiple antigen-binding molecule, its preparation and use |
| 摘要 |
The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.
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| 申请公布号 |
US7838637(B2) |
申请公布日期 |
2010.11.23 |
| 申请号 |
US20040883472 |
申请日期 |
2004.06.30 |
| 申请人 |
AFFITECH RESEARCH AS |
发明人 |
KONTERMANN ROLAND;SEDLACEK HANS-HARALD;MUELLER ROLF |
| 分类号 |
C07K16/00;C12N15/00;A61K31/00;A61K35/74;A61K35/76;A61K38/00;A61K39/00;A61K48/00;A61P7/00;A61P25/00;A61P31/00;A61P35/00;A61P37/00;C07K16/30;C07K16/40;C07K16/46;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/13;C12P21/08 |
主分类号 |
C07K16/00 |
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