发明名称 HEMIN DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF OBTAINING, COMPOSITION AND APPLICATION
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to novel hemin derivatives of general formula I ^ ^ where R1=R2 and represent -alanyl histamine or -gutamyl histamine, or -alanyl histidine, or R1 represents -gutamyl histamine; Y represents CI-; Me represents Fen+, where n=2, 3; and where hemin carboxyl group can be modified with methyl or other C1-8 ether their pharmaceutically acceptable salts; method of their obtaining and pharmaceutical compositions. ^ EFFECT: hemin derivatives of general formula I can be used as artificial nucleases, means, possessing peroxidase activity, catalysts of methyl linoleate oxidation and disinfecting, antiseptic composition, possessing virucidal activity. ^ 9 cl, 1 dwg, 7 tbl, 10 ex
申请公布号 RU2404191(C2) 申请公布日期 2010.11.20
申请号 RU20070125604 申请日期 2007.07.09
申请人 OOO "FARMINTERPRAJSEZ" 发明人 NEBOL'SIN VLADIMIR EVGEN'EVICH;ZHELTUKHINA GALINA ALEKSANDROVNA;LOBANOVA TAT'JANA NIKOLAEVNA;NOSIK NIKOLAJ NIKOLAEVICH;NOSIK DMITRIJ NIKOLAEVICH;ZHELTUKHIN SERGEJ LEONIDOVICH
分类号 A61K38/42;A61P31/00;C07D487/22;C07K14/805 主分类号 A61K38/42
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