发明名称 Proteinaceous binding molecules comprising purification tags or inert variable domains
摘要 The present invention provides proteinaceous binding molecules, in particular antibodies, having at least two variable domains. One variable domain binds to a target molecule of interest. At least one other variable domain comprises a purification tag suitable for purification of said proteinaceous binding molecule. The purification tag enables the convenient purification of the proteinaceous binding molecule with monovalent binding properties against the target molecule.
申请公布号 US2010291078(A1) 申请公布日期 2010.11.18
申请号 US20090812242 申请日期 2009.01.21
申请人 MORPHOSYS AG 发明人 STEIDL STEFAN
分类号 A61K39/395;C07H21/04;C07K16/46;C12N5/10;C12N15/63;G01N33/00 主分类号 A61K39/395
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