Transdermal metformin is an effective alternative treatment modality in patients with insulin resistance who are unable to tolerate other oral anti-diabetic medications. Transdermal metformin can be used in conditions where oral metformin is indicated such as Type 2 diabetes mellitus, pre-diabetes, polycystic ovarian syndrome, and other known diabetes associated disorders. One advantage of using transdermal metformin is its ability to bypass the gastrointestinal system. This allows the drug to not have the gastrointestinal side-effects associated with oral metformin. A surprising advantage of using transdermal metformin in accordance with this disclosure is a 90% decrease in dosage from the oral preparation.
申请公布号
WO2010132562(A2)
申请公布日期
2010.11.18
申请号
WO2010US34542
申请日期
2010.05.12
申请人
OHIO UNIVERSITY;SCARBROUGH, CHASE, A.;SCARBROUGH, STANLEY, S.;SHUBROOK, JAY
发明人
SCARBROUGH, CHASE, A.;SCARBROUGH, STANLEY, S.;SHUBROOK, JAY