发明名称 |
METHODS OF PREVENTING ISCHEMIC INJURY USING PERIPHERAL NOCICEPTIVE STIMULATION |
摘要 |
<p>Methods of inhibiting ischemia-related and ischemia-reperfusion- related injury are provided. Remote administration of a C-fiber activator or TRPV1 agonist or remote electrical stimulation and activation of TRPV1 reduces ischemia-related tissue damage in subjects at risk for Ischemia-related tissue damage, in aspects of the invention, remote application of a TRPV1 agonist inhibits ischemia-related cardiac tissue damage. Methods of inhibiting cardiac tissue damage by topically administering the TRPV1 agonist, capsaicin are provided.</p> |
申请公布号 |
CA2761156(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
CA20102761156 |
申请日期 |
2010.05.07 |
申请人 |
UNIVERSITY OF CINCINNATI |
发明人 |
JONES, W. KEITH;REN, XIAOPING;WEINTRAUB, NEAL LEE |
分类号 |
A01N43/42;A61K31/44 |
主分类号 |
A01N43/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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