| 发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING BCL-2 FAMILY POLYPEPTIDES |
| 摘要 |
The present invention is based, at least in part, on the identification of a novel active site on BCL-2 family polypeptide such as BAX, which when bound by a compound, modifies the activity of the BCL-2 family polypeptide. |
| 申请公布号 |
US2010286057(A1) |
申请公布日期 |
2010.11.11 |
| 申请号 |
US20080680098 |
申请日期 |
2008.09.26 |
| 申请人 |
DANA FARBER CANCER INSTITUTE;NATIONAL INSTITUTES OF HEALTH |
发明人 |
WALENSKY LOREN D.;TJANDRA NICO;GAVATHIOTIS EVRIPIDIS;SUZUKI MOTOSHI;BIRD GREGORY H. |
| 分类号 |
A61P43/00;A61K38/16;C07K14/435;G01N33/53 |
主分类号 |
A61P43/00 |
| 代理机构 |
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