发明名称 ANTIKÖRPER, DIE KREBSERKRANKUNGEN MODIFIZIEREN
摘要 <p>The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.</p>
申请公布号 DE602006017240(D1) 申请公布日期 2010.11.11
申请号 DE20066017240T 申请日期 2006.08.01
申请人 F. HOFFMANN-LA ROCHE AG 发明人 YOUNG, DAVID S. F.;HAHN, SUSAN E.;CECHETTO, LISA M.
分类号 C12P21/08;A61K39/395;A61P35/00;C07K16/18;C07K16/30;C07K16/46;C12N5/16;G01N33/567;G01N33/574 主分类号 C12P21/08
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