发明名称 |
PYRIDINES |
摘要 |
The present invention is concerned with isoxazole-pyridines of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as pharmaceuticals. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
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申请公布号 |
US2010286132(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
US20100768762 |
申请日期 |
2010.04.28 |
申请人 |
JAKOB-ROETNE ROLAND;LUCAS MATTHEW C;THOMAS ANDREW |
发明人 |
JAKOB-ROETNE ROLAND;LUCAS MATTHEW C.;THOMAS ANDREW |
分类号 |
A61K31/541;A61K31/4439;A61K31/444;A61K31/4545;A61K31/5377;A61P25/28;C07D211/60;C07D279/12;C07D413/12;C07D413/14 |
主分类号 |
A61K31/541 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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