MANUFACTURING METHOD OF BIOCOMPATIBLE POLY(VINYL ALCOHOL)-BASED HYDROGEL

摘要

PURPOSE: A manufacturing method of biocompatible poly(vinyl alcohol)-based hydrogel is provided to secure the harmlessness to the human body by avoid using a cross-linking agent without the toxicity. CONSTITUTION: A manufacturing method of biocompatible poly(vinyl alcohol)-based hydrogel comprises a step of freezing and melting a polyvinyl alcohol/hydrophilic polymer aqueous solution containing polyvinyl alcohol and a hydrophilic polymer. The weight average molecular weight of the polyvinyl alcohol is 10,000~1,000,000 g/mol. The freezing time for the freezing step is 1 second~12 hours.