发明名称 TRICYCLIC INHIBITORS OF HYDROXYSTEROID DEHYDROGENASES
摘要 The present invention provides tricyclic compounds according to formula (I): (I) where R1, R2, R3, W, X, Y, Z, m, n, and p are as defined in the description; as well as pharmaceutical compositions comprising the same, methods of use of the compounds and compositions of the invention for the treatment of conditions associated with hydroxysteroid dehydrogenases (e.g., 11-HSD1), and the use of the compounds of the invention in the preparation of medicaments for the treatment of hydroxysteroid dehydrogenase-associated conditions.
申请公布号 US2010280073(A1) 申请公布日期 2010.11.04
申请号 US20080664137 申请日期 2008.06.11
申请人 AMGEN INC. 发明人 POWERS JAY P.;SUN DAQING;YAN XUELEI;JULIAN LISA;GONZALEZ LOPEZ DE TURISO FELIX
分类号 A61K31/454;A61K31/42;A61K31/421;A61K31/426;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P15/00;A61P17/06;A61P19/10;A61P25/24;A61P25/28;A61P27/06;A61P31/12;A61P37/00;C07D261/08;C07D263/32;C07D277/24;C07D413/04;C12N5/02 主分类号 A61K31/454
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