| 发明名称 |
EX-VIVO TREATMENT OF IMMUNOLOGICAL DISORDERS WITH PKC-THETA INHIBITORS |
| 摘要 |
<p>Disclosed is a method for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorders and atherosclerosis. Specifically, the invention relates to a method of treating an immunological disorder or atherosclerosis in a patient comprising treating blood from the patient, or a defined component of said blood, with an inhibitor of PKC-theta ex vivo and then re-administering the treated blood to the patient.</p> |
| 申请公布号 |
WO2010126967(A1) |
申请公布日期 |
2010.11.04 |
| 申请号 |
WO2010US32707 |
申请日期 |
2010.04.28 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;NEW YORK UNIVERSITY;BROWN, MARYANNE;DUSTIN, MICHAEL;ZANIN-ZHOROV, ALEXANDRA |
发明人 |
BROWN, MARYANNE;DUSTIN, MICHAEL;ZANIN-ZHOROV, ALEXANDRA |
| 分类号 |
A61K31/505;A61K39/00;A61P37/00 |
主分类号 |
A61K31/505 |
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