METHOD FOR PRODUCING ISOTHIAZOLE DERIVATIVE

摘要

Disclosed is a method for producing 3,4-dichloro-5-cyanoisothiazole represented by formula (3), comprising reacting a nitrile compound represented by general formula (1) (wherein n represents an integer of 0 to 2) with sulfur chloride represented by general formula (2) (wherein m represents an integer of 1 to 2) in an aprotic polar solvent. A method for producing high-purity 3,4-dichloro-5-cyanoisothiazole without containing tar components, which can be simply performed in an industrial scale in high yield and high efficiency without using a highly toxic starting material while suppressing the generation of waste is provided.