| 发明名称 |
METHOD FOR IMPROVING AMOUNT OF PRODUCED KOJIC ACID BY UTILIZING GENE ESSENTIAL FOR PRODUCTION OF KOJIC ACID |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a microorganism having the improved ability of producing kojic acid by utilizing a gene essential for the production of the kojic acid, and to provide a method for producing the microorganism. <P>SOLUTION: The method for producing the microorganism having the improved ability for producing the kojic acid includes positively regulating the expression levels of one or more genes essential for the production of the kojic acid and selected from the group consisting of specific base sequences in microorganisms, and/or the activity of proteins encoded by the genes. The method for producing the kojic acid by using the microorganisms are also provided. <P>COPYRIGHT: (C)2011,JPO&INPIT |
| 申请公布号 |
JP2010246532(A) |
申请公布日期 |
2010.11.04 |
| 申请号 |
JP20100064965 |
申请日期 |
2010.03.19 |
| 申请人 |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE& TECHNOLOGY;SANSHO SEIYAKU CO LTD;KANAZAWA INST OF TECHNOLOGY |
发明人 |
MACHIDA MASAYUKI;KOIKE HIDEAKI;TERABAYASHI YASUNOBU;YAMANE RINKO;MARUI JUNICHIRO;HIGA YOSHITAKA;TACHIBANA KUNIHARU;OSHIMA EIJI;OHASHI SHINICHI;SANO MOTOAKI;SAGARA JUNICHI;ODA KEN;KITAGAWA HARUE |
| 分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P17/06;C12Q1/68 |
主分类号 |
C12N15/09 |
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