MEANS AND METHODS FOR THE DIFFERENTIATION OF CARDIAC AND DIABETES MELLITUS-BASED CAUSES OF KIDNEY DAMAGE

摘要

The present invention relates to a method for differentiating in a subject suffering from kidney damage between kidney damage caused by (i) heart failure and/or (ii) diabetes mellitus type 1 or type 2 comprising the steps of: a) determining the amount of liver-type fatty acid binding protein (L-FABP) and the amount of kidney injury molecule 1 (KIM-1) in a urine-sample of a subject and forming the L-FABP/KIM-1 ratio; b) determining the amount of adiponectin in a urine-sample of said subject; and c) comparing the ratio determined in a) and the amount determined in b) with reference amounts, and establishing the predominant cause of the kidney damage. Moreover, the present invention relates to a device and a kit for carrying out said method.